Effective renal plasma flow
| Sodium |
Inulin |
Creatinine |
PAH |
| SNa=150 mEq/L |
SIn=1 mg/mL |
SCr=0.01 mg/ml |
SPAH= |
| UNa=710 mEq/L |
UIn=150 mg/mL |
UCr=1.25 mg/mL |
UPAH= |
| CNa=5 mL/min |
CIn=150 ml/min |
CCr=125 mL/min |
CPAH=420 ml/min |
|
|
|
ER=90% |
|
|
|
ERPF=540 ml/min |
Effective renal plasma flow (eRPF) is a measure used in renal physiology[1] to calculate renal plasma flow (RPF) and hence estimate renal function.
Where extraction ratio is the ratio of compound entering the kidney that got excreted into the final urine.
When using a compound with an extraction ratio near 1, such as para-aminohippurate (PAH), then eRPF is almost equal to RPF. Therefore, PAH clearance is a method to estimate renal plasma flow.
References